Feb. 24, 2019 Updated

Our research goal is the creation of medical nanomachines/devices to provide novel therapeutic modalities for treatment of intractable diseases. Particularly, we have developed polymer self-assemblies for drug and nucleic acid delivery.

To realize nucleotide therapeutics, nucleic acids need to be efficiently delivered to the cytoplasm of target cells. Precise designs of polymeric materials enable the creation of smart nanomachines/devices that can exert the desired functions at the desired sites to overcome various biological barriers for successful nucleic acid delivery.

One of the most interesting things in this "NanoBio" research is the dramatic improvement in the therapeutic efficacy of nanomachines/devices by a slight change in the material design.

Miyata laboratory
The University of Tokyo, Department of Materials Engineering, Bld.#4, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656